Rabies immunoglobulin is used together with rabies vaccine to help protect you against infection caused by rabies virus.
Rabies is a deadly virus that can cause brain inflammation. It is spread to people from the saliva of infected animals usually through a bite.
Rabies immunoglobulin is preferably given by injection into and around the cleansed wound. If injecting the full dose into or around the wound is not possible, any remaining dose may be given intramuscularly (into the muscle), usually into the muscles of the upper arm or thigh.
Your doctor or nurse will administer the injection for you.
Inform your doctor if you have the following conditions:
- history of allergic reactions after being injected with other medicines known as immunoglobulins from humans or horse serum
- bleeding disorders
- conditions that increase the risk of forming blood clots e.g. history of blood clots, prolonged immobilisation, high blood pressure, heart disease, diabetes
- inflammatory conditions
- immunoglobulin A deficiency (a condition wherein the body lacks a sufficient number of immunoglobulin A, a specific blood protein that fights infection)
Let your doctor know if you are pregnant or breastfeeding.
Be sure to check with your doctor or pharmacist before giving Rabies immunoglobulin to a child. Children may be more sensitive to the side effects.
Inform your doctor if you have been recently vaccinated, particularly if you have previously received a rabies vaccine. Do not receive any vaccinations without first asking your doctor.
If you are going to have a certain laboratory test (e.g. blood test to detect antibodies against red blood cells), inform your doctor that you have been given a Rabies immunoglobulin.
Keep your appointments with your doctor. Your doctor needs to monitor your condition regularly.
Rabies immunoglobulin may cause any of the following side effects: headache, dizziness, nausea, vomiting, diarrhoea, stomach wind, stomach pain, stuffy or clogged nose, fever, joint or muscle pain, tiredness, and pain, swelling, bruising, redness or warmth at the injection site.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- signs and symptoms of allergic reactions e.g. rashes, breathlessness, swelling of the face, eyes or mouth
- signs and symptoms of blood clots e.g. shortness of breath, chest pain, cough which may contain blood, pain or swelling in your leg accompanied by redness and warmth
- signs and symptoms of a certain red blood cell problem e.g. chills, fever, dark urine
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Avoid vaccinations with live attenuated vaccines after treatment with Rabies immunoglobulin. Alert your doctor if you have been recently vaccinated or if you are planning to get vaccinated.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
Avoid alcohol.
Store in the refrigerator, between 2-8°C.
Do not freeze Rabies immunoglobulin otherwise, it will no longer be effective and should not be used.
Protect from light.
Medicines must not be used past the expiry date.
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